Statins: New Study Eases Side Effect Concerns

Health Points

• Recent research shows statins do not cause most of the side effects typically listed on packaging.
• Experts say the cardiovascular benefits of statins far outweigh the risks for most people.
• Only a few mild side effects showed an increase in those taking statins, with serious issues remaining rare.

A new University of Oxford study offers reassuring news for adults with high cholesterol considering statin therapy. Researchers found that most side effects you might worry about—like fatigue, weight gain, and mood changes—are just as likely to occur in people taking a placebo as those on statins.

“Statins are potentially life-saving drugs, and many people deny themselves of their potential benefits for fear of side effects,” explained Dr. Michael D. Shapiro, director of the Center for Preventive Cardiology at Wake Forest Baptist Health.

In an analysis of over 124,000 participants, only mild increases in liver blood test changes and small shifts in urine composition and swelling were found, without leading to serious health concerns. Muscle aches, often cited as a worry, were only seen slightly more frequently than in those given placebos and mainly during the first year.

Statins can rarely cause serious muscle problems, but this is extremely uncommon, affecting about one in 10,000 people, according to lead researcher Dr. Christina Reith. Some people may also notice a slight rise in blood sugar, though new diabetes mainly developed in those already at higher risk.

Dr. Shapiro added, “Most symptoms commonly attributed to statins occur at the same rate in people taking placebo, meaning they are not caused by the medication.”

Experts recommend talking to your doctor to discuss your cholesterol, individual risk, and the best course for your heart health. For the vast majority of patients, the protective effects of statins far exceed the chance of side effects, helping reduce the risk of heart attack and stroke.

Take charge of your health—if you have questions about statins or your cholesterol, consult your healthcare provider to make informed choices for your wellness journey.

Read more at Health.com