Health
Artificial Sweeteners Linked to Memory Risks
Health Points
- A large study linked low- and no-calorie sweeteners to cognitive decline, especially in adults under 60.
- Sweeteners studied included aspartame, saccharin, acesulfame-K, erythritol, sorbitol, xylitol, and tagatose; those with diabetes saw stronger effects.
- Experts recommend moderation and a diet rich in whole, plant-based foods for long-term brain health.
Recent research highlights a potential connection between consuming artificial sweeteners and memory decline, mainly in people younger than 60. While these sugar substitutes can help with calorie reduction, dental health, and blood sugar control, they may also come with unexpected risks for your mind.
The study tracked over 12,000 Brazilian adults for eight years, focusing on seven commonly used sweeteners. Researchers observed that those using more artificial sweeteners experienced greater declines in memory and overall thinking skills—especially participants with diabetes.
“We used the sweeteners that were available in Brazil at the time (of enrollment),” Dr. Claudia Suemoto says. “Unfortunately, some sweeteners, like sucralose and stevia, were not available.”
The effect was more noticeable in adults under 60, suggesting that midlife dietary habits could shape brain health decades later. Scientists are still exploring how sweeteners might affect the brain, considering factors like inflammation and gut health, but most animal studies use extreme doses not typical of daily consumption.
“Animal studies, for example, suggest that aspartame can trigger inflammation in the brain, while sugar alcohols like erythritol and sorbitol may alter gut microbes and compromise the blood–brain barrier,” Dr. Suemoto explains.
As the evidence is still emerging, experts recommend limiting artificial sweeteners and focusing on whole, plant-based foods for better overall wellness. Maintain a balanced diet with leafy greens, colorful fruits, nuts, and whole grains to support brain health as you age.
Looking for swaps? Try sparkling water with fruit instead of diet soda, or stir fresh berries into plain yogurt for a tasty, brain-friendly snack.
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