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Surgery Surpasses GLP-1 for Weight Loss

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Health Points

  • Confirm surgical eligibility before choosing a path.
  • Review insurance and long-term costs when planning therapy.
  • Plan lifelong follow-up after surgery to monitor nutrition and health.

A large new study found that people who had sleeve gastrectomy or gastric bypass lost about 24% of their body weight—roughly 58 pounds on average—two years after surgery, while patients prescribed GLP-1 drugs lost about 5%, or 12 pounds on average.

The research compared 38,545 people taking GLP-1 medications with 12,540 patients who underwent bariatric procedures, and authors say decisions should be individualized based on eligibility, goals and risks.

“Clinical trials show weight loss between 15-21% for GLP-1s, but this study suggests that weight loss in the real world is considerably lower,” Dr. Avery Brown said.

“We have to take the prescribing of them much more seriously. I don’t think we can be giving them out like candy,” Dr. Karan Chhabra said.

Talk with your clinician about which option fits your health goals, eligibility and lifestyle before deciding.

Read the full Today report

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